UNIVERSITA' DEGLI STUDI DI BARI
Leonardo Degennaro
Dipartimento Farmaco Chimico
Università di Bari
Via E. Orabona,
4
I-70125 Bari (Italy).
Tel: +39.080.5442773
Fax:
+39.080.5442539
E-mail: dinodegennaro@hotmail.com
Personal
information:
DATE OF BIRTH: July 04th
1972
PLACE OF BIRTH: Bitonto (Italy)
CITIZENSHIP: Italian
Education:
University of Bari,
Pharmaceutical-Chemistry Department, Italy
Ph. D.Student, II year, Chemical
and Enzymatic applied Synthesis
Thesis advisor: Prof. Saverio
Florio.
University of Bari,
Faculty of Pharmacy, Italy
BS 107/110, Pharmaceutical Chemistry and
Technology
July 1999, Thesis advisor: Prof. Saverio
Florio.
Skills:
- Proficient
user of 1H and 13C FT-NMR, FT-IR, UV-vis spectrometer,
GC-MS, analytical and preparative HPLC.
- languages: Italian, English and
French.
Professional Experience:
- September 1999 - December 1999:
Fellowship of Dipartimento Farmaco-Chimico –University of Bari – with
Prof. S. Florio. Field of interest: “Reactivity of functionalizated
oxiranes”.
- Winter 1996 - Winter 1998: Thesis research in Organic
Chemistry with Prof. Saverio Florio at University of Bari. “Synthesis and
reactivity of optically active 2-Chloroalkyl-oxazolines”.
- Winter
1999 - Winter 2000: Obbligatory National Service in the Italian Army as
Artillery soldier.
Research
Activity:
Asymmetric synthesis by using chiral non
racemic metallated oxazolines and oxazolinyloxiranyl lithiums.
Couplings of lithiated oxazolines
with nitrones: synthesis of oxazolinylalkenes and
oxazolinyloxazetidines.
Schools and
Courses:
1)
3rd Italian German Symposium on Organic Chemistry, March 30 – April 1,
2001, Ravenna, Italy. Poster presentation
2) XXVII Conference
National of Italian Organic Chemistry Division, 3-7 september, Trieste, Italy.
Poster presentation
3) Seminars in Organic Synthesis, XXVI Summer
School “A. Corbella” 18-22 Jun. 2001, Gargnano - Italy.
Publications:
1) Saverio Florio, Vito Capriati,
Renzo Luisi, Leonardo Degennaro
“A highly
stereoselective synthesis of a,b-unsaturated
oxazolines”
Tetrahedron
Lett. 2001, 42, 9183-9186.
2) Saverio Florio, Vito Capriati, Renzo Luisi,
Alessandro Abbotto, Leonardo Degennaro and Antonio
Salomone
“A stereospecific: Synthesis of
Oxazolinyloxiranes”
J. Org. Chem. 2001, 66,
3049-3058.
3) Saverio Florio, Vito Capriati, Renzo Luisi, Leonardo
Degennaro, Carmela Tralli, Luigino Troisi
“Lithiation of
2-(1-Chloroethyl)-2-oxazolines: “Synthesis of substituted oxazolinyloxiranes and
oxazolinylaziridines”.
Synthesis. 2001, 15,
2299-2306.
4) Vito Capriati, Leonardo Degennaro, Saverio Florio, and
Renzo Luisi
“On the Addition of Lithiated
2-Alkyl- and 2-(Chloroalkyl)-4,5-dihydro-1,3-oxazoles to Nitrones – A
Mechanistic Investigation”
Eur. J. Org. Chem. 2002,
2961-2969.
5) Vito
Capriati, Leonardo Degennaro, Raffaele Favia, Saverio Florio and Renzo
Luisi
"Stereospecific b-lithiation of
oxazolinyloxiranes: Synthesis of a,b-epoxy-g-butyrolactones"
Org. Lett. 2002, 1551-1554.
6) Renzo Luisi, Vito Capriati, Leonardo Degennaro,
Saverio Florio
“Oxazolinyloxiranyllithium-Mediated Stereoselective Synthesis of a-Epoxy-b-Amino
Acids”
Org. Lett. 2003, 5 (15) 2723–2726.
7) Renzo Luisi,
Vito Capriati, Claudia Carlucci, Leonardo Degennaro, Saverio
Florio
“Lithiation of
Optically Active Oxazolinyloxiranes: Configurational Stability”
Tetrahedron 2003, 59, 9707–9712.
8) Renzo Luisi,
Vito Capriati, Leonardo Degennaro, Saverio Florio
“Oxazolinyloxiranyllithium-Mediated Synthesis of Highly Strained Hetrocyclic
Compounds”
Tetrahedron 2003, 59, 9713–9718 .
9) Saverio Florio,
Vito Capriati, Leonardo Degennaro, Renzo Luisi, Filippo Maria
Perna
"Novel
oxazoline-mediated Syntheses of heterocycles" Oxygen-and Sulfur-Containing
Heterocycles, The Chemistry and Biological Activity of
Synthetic
and Natural Compounds, IBS Press, 2003, Vol
1, 66.