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          <TD class=copy><!-- // End mixed JSP/HTML code segment -->• 
            Professor, Center for Systems Biology - DBI <BR><IMG height=2 alt="" 
            src="9.files/spacer.gif" width=1><BR>• William L. Friend Professor 
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            alt="" src="9.files/spacer.gif" width=1><BR><IMG height=10 alt="" 
            src="9.files/spacer.gif" width=1><BR>Department of Chemical 
            Engineering<BR>University of Delaware<BR>Newark, Delaware 
            19716<BR><IMG height=5 alt="" src="9.files/spacer.gif" 
            width=1><BR>302-831-4504<BR>302-831-1048 fax<BR><IMG height=5 alt="" 
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            href="mailto:ogunnaik@che.udel.edu">ogunnaik@che.udel.edu</A><BR><IMG 
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    <TD class=copy colSpan=3>For More Info About <B>Current Research 
      Projects</B> <A href="http://www.che.udel.edu/systems/">Click Here</A> 
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      <P class=copy><IMG height=15 alt="" src="9.files/spacer.gif" width=1><BR>" 
      Our research efforts are organized around the general theme of first 
      understanding the dynamic behavior of complex systems through mathematical 
      modeling and analysis, and then exploiting this understanding for novel 
      designs and improved operation. The particular complex systems of interest 
      range from polymer reactors, particulate processes and extruders, to 
      biological systems on the cellular, tissue, and organ levels. When 
      sufficient fundamental knowledge is available, we develop and employ 
      dynamic “mechanistic” models; when more data is available than fundamental 
      knowledge, we apply probability theory and statistics for efficient data 
      acquisition and “empirical” model development. Our research group has 
      three main areas of focus: 1. Control and systems theory, where we are 
      concerned with the development of effective control techniques, with 
      application to industrial polymer reactors, distillation columns, 
      particulate processes, and reactive extrusion processes; we are also 
      interested in reverse engineering biological control systems for process 
      applications. 2. Systems biology, where we bring principles of control and 
      systems theory as well as probabilistic/statistical techniques to bear on 
      the analysis of biological processes. We are developing models, tools and 
      techniques to study biological systems across various levels of 
      granularity—from the molecular level where mechanistic details at the 
      genetic and protein levels are studied, to the cellular, tissue, organ and 
      physiological system level. The goals of our systems biology efforts are 
      to be able to understand, analyze and predict integrated biological 
      systems function with sufficient fidelity for potential practical medical 
      and pharmaceutical applications. 3. Product engineering, Process design 
      and operations, where we employ both stochastic and deterministic 
      techniques for engineering desired characteristics into products, and 
      subsequently for developing inherently robust processes to manufacture 
      these products to meet customer demands consistently in the face of 
      unavoidable process and raw material variations. " </P>
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      <A HREF="http://copland.udel.edu/~sherrill/">For More Info
        About <b>Current Research Projects</b> Click Here</A>
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